Introduction

Poly-MVA is a promising new dietary supplement that may assist in boosting immune response, and healing damaged cells. It is a uniquely formulated nutritional supplement containing a proprietary blend of Palladium and alpha-lipoic Acid (which we refer to as LAPd), Vitamins B1, B2 and B12, Formylmethionine, Acetyl Cystiene, and trace amounts of Molybdinum, Rhodium, and Ruthenium. It is designed to provide energy for compromised body systems by changing the electrical potential of human cells, increasing the charge density of DNA within the cell.

Poly-MVA is a new, non-toxic, powerful antioxidant dietary supplement. While definitive studies on it's effect in human nutrition and health are under way, early studies and anecdotal information indicate that the active ingredients in Poly-MVA may be beneficial in protecting cell DNA and RNA, assisting the body produce energy, and provide support to the liver in removing harmful substances from the body. Some studies indicate that ingredients of Poly-MVA can assist in preventing cell damage, and removing heavy metals from the bloodstream. As a powerful antioxidant, it can help to neutralize the free radicals within the body that are thought to influence the aging processes and convert them into energy. Other ingredients are involved in DNA synthesis, production of the myelin sheath that protects nerves, and red blood cell production, and playing an important role in immune and nerve function.

What makes Poly-MVA unique is the special, proprietary manufacturing process by which lipoic acid is bonded to Palladium (LAPd). No other company produces any product similar to Poly-MVA because of the patented preparation and bonding process through which LAPd is manufactured. The proprietary formulation of LAPd with other vitamins, minerals, and amino acids provides considerable nutritional support, helping to enable optimum functioning of essential body systems.

Poly-MVA can provide the following nutritional support to the body:

Helps the body to produce energy
Supports the liver in removing harmful substances from the body
Assists in preventing cell damage
Assists the body in removing heavy metals from the bloodstream

Powerful antioxidant and detoxificant
Prevents B-12 deficiency related mental disturbances in the elderly
Supports nerve and neurotransmitter function
Enhances white blood cell function
Supports pH balance, helping to maintain oxygenation of cells and tissues
*Although not all scientific studies have been completed, a significant number of articles in peer reviewed scientific and medical journals discuss the possible biochemical significance of LAPd in supporting various biological functions within animals and humans. Additionally, some studies have already been planned or are currently underway to further evaluate the value and effectiveness of LAPd in human nutrition.

Dr. Merrill Garnett

Merrill Garnett is a doctor and research chemist, head of the Garnett McKeen Laboratory, in Stony Brook, New York. Dr. Garnett is the inventor and recipient of multiple U.S. patents for palladium lipoic complexes. For nearly 40 years, Dr. Garnett has probed the secrets of molecular biology and the mysteries of cells. He saw cellular dysfunction as the failure of cells to regenerate normally in a default mode; instead, cloning itself in a deranged state over and over again. He theorized that this failure to mature was a problem of energetics in the cells metabolic processes. The cells energy transport chain which occurs through electron transfer.

Dr. Garnett began the often lonely search to find a molecular compound that would restore healthy pathways for growth and normal development within the cell-pathways missing or deficient in dysfunctional cells. He searched for a natural metallo-organic compound that would act as a molecular shunt to restore the cells healthy energetics. After testing some 20,000 compounds, Dr. Garnett developed the biochemical formula that became Poly-MVA in 1991. He discovered that palladium combined with lipoic acid, B-12 and thiamine created an extremely useful and safe cellular nutrient. Subsequent tests have shown that Poly MVA is safe and nontoxic, and Dr. Garnett is currently working in cooperation with other researchers to determine the effectiveness of principal ingredients of Poly-MVA for other uses.

Poly-MVA: A Patented Metallo-vitamin

When lipoic acid, a powerful antioxidant with many biological functions, is connected to an electrically charged metal substrate, and joined with various B vitamins, the resulting complex becomes totally soluble in both water and fat. It can easily and safely travel throughout the body and into every cell, crossing the blood-brain barrier as well. Therefore, performing that journey across the blood-brain barrier (impossible even for most drugs, let alone ordinary nutritional supplements) suggests that the nutritonal supplement Poly-MVA, may hold great promise in cases where other means of supplementing cell nutrition are ineffective.

In addition to his work with Poly-MVA, Merrill Garnett with help from his son, Wade, is also developing "electro-active" compounds that destroy certain malignant tumors without damaging healthy cells. The Garnetts' research is based on the theory that all normally developed cells contain an inward directed energy flow. They have looked for those pathways which alter electron flow in the cell, from the point of view that normal development requires normal energy flow. In laboratory experiments, the Garnetts found that by introducing synthetic mimics of electric pathways, dysfunctional cells are changed selectively, either back to normalcy or they can not survive.

The Poly-MVA dietary supplement developed by the Garnetts works because healthy cells have "oxygen radical pathways." Normally, oxygen radicals are formed when fatty acids donate electrons to oxygen. These oxygen radicals have an unpaired electron charge and are unstable. Special proteins, in the mitochondria, convert the oxygen radicals into water and useable energy. At the Garnett McKeen Laboratory in New York, the Garnetts are producing synthetic mimics of electric pathways by introducing palladium lipoic complexes in various combinations into cells. For more information on Garnett-McKeen Labs, visit www.electrogenetics.com.

Safe and Non-Toxic

Palladium lipoic complexes have been extensively tested under laboratory conditions and have been used for more than eight years as a dietary supplement. Animal toxicology and safety studies indicate that palladium lipoic complex is safe even when administered at very high levels.

Fast-acting

Since Poly-MVA is easily absorbed by the body, most individuals notice a difference in how they feel within 2-4 weeks. Some individuals have seen positive results (i.e. energy improvement and increased appetite) in a matter of days.

Individual ingredients of Poly-MVA

Click here to view Poly-MVA label

The alpha-lipoic acid ("LA") in Poly-MVA (also known as thioctic acid) works together with other antioxidants such as Vitamins C and E. LA helps the body to produce energy, and provides support to the liver in removing harmful substances from the body. Some studies indicate that LA assists in preventing cell damage, and removing heavy metals from the bloodstream. Because of its strong detoxificant effects, LA is commonly used in the treatment of Amanita mushroom poisoning, which causes severe liver damage. LA also influences the metabolism of sugar, and can help to keep blood sugar in balance.

Diabetics seem to receive particular benefit from this substance. Alpha lipoic acid helps ward off diabetic neuropathy (painful extremities) and retinopathy (a common cause of blindness). It also helps regulate blood sugar and prevent cardiomyopathy. Alpha lipoic acid may even be involved in nerve regeneration. Promising studies are underway to determine its value in retarding the onset of Alzheimer's and Parkinson's Diseases.

As a powerful antioxidant, LA can help to neutralize the free radicals within the body that are thought to influence aging processes. LA is both water and fat soluble, so it is easily passed across the blood-brain barrier, and is functional in almost all other parts of the body as well.

Vitamin B-12 is also known as cobalamin. It's most common form is cyanocobalamin, which is broken down to methylcobalamin by the body. It is generally found only in meat and dairy products. In combination with folic acid, B-12 is involved in DNA synthesis, production of the myelin sheath that protects nerves, and red blood cell production. As a methyl donor involved in homocysteine metabolism, B-12 also plays an important role in immune and nerve function.

B-12 deficiency is fairly common in those over 65, and because it is stored in organs, deficiencies can take a very long time - up to 6 years - to appear. Worse, deficiencies of B12 or folic acid (a complementary substance necessary for B-12 utilization) can result in significant mental disturbances without any indication of anemia or other clinical indication of deficiency. In patients with B-12 deficiency, up to 61% have shown a marked increase in mental capacity when B-12 supplements are added to the diet.

Taken orally, B-12 is absorbed at a rate of about 1.2% according to most studies. Since the body uses about 2 mcg of B-12 daily, 200 mcg orally administered will maintain B-12 levels at stasis. For those who are deficient, a higher supplementation level will be required.

Vitamin B-1 (thiamin) is a coenzyme that, in combination with lipoic acid, is involved in the decarboxylation of pyruvate and the oxidation of alpha keto-glutamic acid. These functions are essential to energy production, metabolism of carbohydrates, and neurotransmitter function. B-1 is extremely sensitive to alcohol, sulfites, and tannins found in black tea and coffee; all will render B-1 ineffective. B-1 is water soluble and is not stored in any quantities in the body.

Extreme B-1 deficiency, which is rare in most developed countries, causes beriberi, a syndrome whose symptoms include loss of muscle, mental confusion, elevated blood pressure, and edema. Milder deficiencies can cause fatigue, depression, tingling or numbness in the extremities, and constipation. Research in animals indicates that B-1 activates membrane ion channels, possibly by phosphorylating them. The flow of electrolytes like sodium and chloride in or out of nerve and muscle cells through membrane ion channels plays a role in nerve impulse conduction and voluntary muscle action.

Vitamin B2 (riboflavin) acts as a cofactor for enzymes involved in metabolism. It is an essential part of FAD or flavin adenine dinucleotide coenzymes and FMN or flavin mononucleotide. These coenzymes are involved in energy production and the metabolism of protein, fat and carbohydrate ø essential processes in every cell in the body. They are also cofactors for two important antioxidant enzyme systems ø glutathione peroxidase and xanthine oxidase. Riboflavin coenzymes are also important in the cytochrome p450 enzymes, the body's primary detoxification system.B2) works with the other B vitamins and is important for body growth and red cell production. Similar to thiamine, it helps in releasing energy from carbohydrates.

Molybdenum is an essential trace mineral. It is crucial in regulating pH balance in the body, which, in turn, directly effects oxygenation of cells and tissues, and the resulting metabolic rate of the body. The need for molybdenum has been established, but there is presently no recommended daily allowance.

N-Acetyl Cystiene (NAC) is an amino acid naturally occurring in the body. It is a potent antioxidant that is involved in maintenance of cholesterol and lipoprotein levels, and functions in combination with natural interferons in the body to enhance immune response. NAC is an amino acid derivative, which has begun to receive increasing attention as a powerful free radical scavenger. This simple compound has an extremely low profile of side effects and helps the body in a variety of ways. It enhances the activity of Vitamins C & E. It enhances the immune system, improves lung function, helps transport sterol hormones, helps prevent insulin resistance, and prevents ammonia formation.

Further Research